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Impact of post-alignment processing in variant discovery from whole exome data
BACKGROUND: GATK Best Practices workflows are widely used in large-scale sequencing projects and recommend post-alignment processing before variant calling. Two key post-processing steps include the computationally intensive local realignment around known INDELs and base quality score recalibration...
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| Foilsithe in: | BMC Bioinformatics |
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| Main Authors: | , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
BioMed Central
2016
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5048557/ https://ncbi.nlm.nih.gov/pubmed/27716037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1279-z |
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