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An Integrated Human/Murine Transcriptome and Pathway Approach To Identify Prenatal Treatments For Down Syndrome

Anatomical and functional brain abnormalities begin during fetal life in Down syndrome (DS). We hypothesize that novel prenatal treatments can be identified by targeting signaling pathways that are consistently perturbed in cell types/tissues obtained from human fetuses with DS and mouse embryos. We...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Guedj, Faycal, Pennings, Jeroen LA, Massingham, Lauren J., Wick, Heather C., Siegel, Ashley E., Tantravahi, Umadevi, Bianchi, Diana W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009456/
https://ncbi.nlm.nih.gov/pubmed/27586445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32353
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