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The Fetal Brain Transcriptome and Neonatal Behavioral Phenotype in the Ts1Cje Mouse Model of Down syndrome
Human fetuses with Down syndrome demonstrate abnormal brain growth and reduced neurogenesis. Despite the prenatal onset of the phenotype, most therapeutic trials have been conducted in adults. Here, we present evidence for fetal brain molecular and neonatal behavioral alterations in the Ts1Cje mouse...
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| Publicado no: | Am J Med Genet A |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4844354/ https://ncbi.nlm.nih.gov/pubmed/25975229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.37156 |
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