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The Fetal Brain Transcriptome and Neonatal Behavioral Phenotype in the Ts1Cje Mouse Model of Down syndrome
Human fetuses with Down syndrome demonstrate abnormal brain growth and reduced neurogenesis. Despite the prenatal onset of the phenotype, most therapeutic trials have been conducted in adults. Here, we present evidence for fetal brain molecular and neonatal behavioral alterations in the Ts1Cje mouse...
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| Опубликовано в: : | Am J Med Genet A |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4844354/ https://ncbi.nlm.nih.gov/pubmed/25975229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.37156 |
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