Clustering of transcriptional profiles identifies changes to insulin signaling as an early event in a mouse model of Alzheimer’s disease

Por Jackson, Harriet M, Soto, Ileana, Graham, Leah C, Carter, Gregory W, Howell, Gareth R
Publicado em 2013

Deficiency of complement component 5 ameliorates glaucoma in DBA/2J mice

Por Howell, Gareth R, Soto, Ileana, Ryan, Margaret, Graham, Leah C, Smith, Richard S, John, Simon WM
Publicado em 2013

Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer’s disease

Por Graham, Leah C., Harder, Jeffrey M., Soto, Ileana, de Vries, Wilhelmine N., John, Simon W. M., Howell, Gareth R.
Publicado no Sci Rep (2016)

Meox2 haploinsufficiency increases neuronal cell loss in a mouse model of Alzheimer's disease

Por Soto, Ileana, Grabowska, Weronika A., Onos, Kristen D., Graham, Leah C., Jackson, Harriet M, Simeone, Stephen N., Howell, Gareth R.
Publicado no Neurobiol Aging (2016)

The Fetal Brain Transcriptome and Neonatal Behavioral Phenotype in the Ts1Cje Mouse Model of Down syndrome

Por Guedj, Faycal, Pennings, Jeroen L. A., Ferres, Millie A., Graham, Leah C., Wick, Heather C., Miczek, Klaus A., Slonim, Donna K., Bianchi, Diana W.
Publicado no Am J Med Genet A (2015)

APOE Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction

Por Soto, Ileana, Graham, Leah C., Richter, Hannah J., Simeone, Stephen N., Radell, Jake E., Grabowska, Weronika, Funkhouser, W. Keith, Howell, Megan C., Howell, Gareth R.
Publicado no PLoS Biol (2015)

DBA/2J Genetic Background Exacerbates Spontaneous Lethal Seizures but Lessens Amyloid Deposition in a Mouse Model of Alzheimer’s Disease

Por Jackson, Harriet M., Onos, Kristen D., Pepper, Keating W., Graham, Leah C., Akeson, Ellen C., Byers, Candice, Reinholdt, Laura G., Frankel, Wayne N., Howell, Gareth R.
Publicado no PLoS One (2015)

TREM2 deficiency eliminates TREM2(+) inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models

Por Jay, Taylor R., Miller, Crystal M., Cheng, Paul J., Graham, Leah C., Bemiller, Shane, Broihier, Margaret L., Xu, Guixiang, Margevicius, Daniel, Karlo, J. Colleen, Sousa, Gregory L., Cotleur, Anne C., Butovsky, Oleg, Bekris, Lynn, Staugaitis, Susan M., Leverenz, James B., Pimplikar, Sanjay W., Landreth, Gary E., Howell, Gareth R., Ransohoff, Richard M., Lamb, Bruce T.
Publicado no J Exp Med (2015)