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Meox2 haploinsufficiency increases neuronal cell loss in a mouse model of Alzheimer's disease

Evidence suggests that multiple genetic and environmental factors conspire together to increase susceptibility to Alzheimer's disease (AD). The amyloid cascade hypothesis states that deposition of the amyloid-β peptide is central to AD; however, evidence in humans and animals suggests that amyl...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Soto, Ileana, Grabowska, Weronika A., Onos, Kristen D., Graham, Leah C., Jackson, Harriet M, Simeone, Stephen N., Howell, Gareth R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878023/
https://ncbi.nlm.nih.gov/pubmed/27143421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2016.02.025
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