DBA/2J Genetic Background Exacerbates Spontaneous Lethal Seizures but Lessens Amyloid Deposition in a Mouse Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is a leading cause of dementia in the elderly and is characterized by amyloid plaques, neurofibrillary tangles (NFTs) and neuronal dysfunction. Early onset AD (EOAD) is commonly caused by mutations in amyloid precursor protein (APP) or genes involved in the processing of APP...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Jackson, Harriet M., Onos, Kristen D., Pepper, Keating W., Graham, Leah C., Akeson, Ellen C., Byers, Candice, Reinholdt, Laura G., Frankel, Wayne N., Howell, Gareth R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416920/
https://ncbi.nlm.nih.gov/pubmed/25933409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125897
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk