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Analysis of Adult Cerebral Cortex and Hippocampus Transcriptomes Reveals Unique Molecular Changes in the Ts1Cje Mouse Model of Down Syndrome

We investigated gene expression and functional differences between Ts1Cje mice and wild‐type (WT) littermates in adult cerebral cortex and hippocampus. These two brain regions are affected in people with Down syndrome, but have not been previously molecularly characterized in Ts1Cje mice. Total RNA...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Guedj, Faycal, Pennings, Jeroen L. A., Wick, Heather C., Bianchi, Diana W.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029241/
https://ncbi.nlm.nih.gov/pubmed/24916381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12151
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