Analysis of Adult Cerebral Cortex and Hippocampus Transcriptomes Reveals Unique Molecular Changes in the Ts1Cje Mouse Model of Down Syndrome

We investigated gene expression and functional differences between Ts1Cje mice and wild‐type (WT) littermates in adult cerebral cortex and hippocampus. These two brain regions are affected in people with Down syndrome, but have not been previously molecularly characterized in Ts1Cje mice. Total RNA...

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Vydáno v:Brain Pathol
Hlavní autoři: Guedj, Faycal, Pennings, Jeroen L. A., Wick, Heather C., Bianchi, Diana W.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2014
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029241/
https://ncbi.nlm.nih.gov/pubmed/24916381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12151
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