Induction of the mesenchymal to epithelial transition by demethylation-activated microRNA-125b is involved in the anti-migration/invasion effects of arsenic trioxide on human chondrosarcoma

BACKGROUND: In addition to treating acute promyelocytic leukemia, arsenic trioxide (ATO) suppresses other solid tumors, including chondrosarcoma. However, the effects of ATO on metastasis in chondrosarcoma cells, and the underlying molecular mechanisms remain unclear. METHODS: The effects of ATO on...

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書目詳細資料
發表在:J Exp Clin Cancer Res
Main Authors: Bao, Xing, Ren, Tingting, Huang, Yi, Wang, Shidong, Zhang, Fan, Liu, Kuisheng, Zheng, Bingxin, Guo, Wei
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006509/
https://ncbi.nlm.nih.gov/pubmed/27576314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0407-y
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