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Induction of the mesenchymal to epithelial transition by demethylation-activated microRNA-125b is involved in the anti-migration/invasion effects of arsenic trioxide on human chondrosarcoma

BACKGROUND: In addition to treating acute promyelocytic leukemia, arsenic trioxide (ATO) suppresses other solid tumors, including chondrosarcoma. However, the effects of ATO on metastasis in chondrosarcoma cells, and the underlying molecular mechanisms remain unclear. METHODS: The effects of ATO on...

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Détails bibliographiques
Publié dans:J Exp Clin Cancer Res
Auteurs principaux: Bao, Xing, Ren, Tingting, Huang, Yi, Wang, Shidong, Zhang, Fan, Liu, Kuisheng, Zheng, Bingxin, Guo, Wei
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006509/
https://ncbi.nlm.nih.gov/pubmed/27576314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0407-y
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