Knockdown of long non-coding RNA HOTAIR increases miR-454-3p by targeting Stat3 and Atg12 to inhibit chondrosarcoma growth

Current practices for the therapy of chondrosarcoma, including wide-margin surgical resection and chemotherapy, are less than satisfactory. Recently, emerging evidence has demonstrated that long non-coding RNAs (lncRNAs) have an essential role in the initiation and progression of tumors. As a typica...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Bao, Xing, Ren, Tingting, Huang, Yi, Sun, Kunkun, Wang, Shidong, Liu, Kuisheng, Zheng, Bingxin, Guo, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386479/
https://ncbi.nlm.nih.gov/pubmed/28182000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.31
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