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Bisulfite oligonucleotide-capture sequencing for targeted base- and strand-specific absolute 5-methylcytosine quantitation

Epigenetic regulation through DNA methylation (5mC) plays an important role in development, aging, and a variety of diseases. Genome-wide studies of base- and strand-specific 5mC are limited by the extensive sequencing required. Targeting bisulfite sequencing to specific genomic regions through sequ...

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Detalhes bibliográficos
Publicado no:Age (Dordr)
Main Authors: Masser, Dustin R., Stanford, David R., Hadad, Niran, Giles, Cory B., Wren, Jonathan D., Sonntag, William E., Richardson, Arlan, Freeman, Willard M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5005917/
https://ncbi.nlm.nih.gov/pubmed/27091453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-016-9914-1
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