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Revisiting the genomic hypomethylation hypothesis of aging

The genomic hypomethylation hypothesis of aging proposes that an overall decrease in global DNA methylation occurs with age, and it has been argued that the decrease in global DNA methylation could be an important factor in aging, resulting in the relaxation of gene expression regulation and abnorma...

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Detalhes bibliográficos
Publicado no:Ann N Y Acad Sci
Main Authors: Unnikrishnan, Archana, Hadad, Niran, Masser, Dustin R., Jackson, Jordan, Freeman, Willard M., Richardson, Arlan
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934293/
https://ncbi.nlm.nih.gov/pubmed/29363785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.13533
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