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The role of DNA methylation in epigenetics of aging

Recent research suggests that epigenetics, especially DNA methylation, plays a mechanistic role in aging. Epigenetic clocks, which measure changes in a few hundred specific CpG sites, can accurately predict chronological age in a variety of species, including humans. These clocks are currently the b...

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Detalhes bibliográficos
Publicado no:Pharmacol Ther
Main Authors: Unnikrishnan, Archana, Freeman, Willard M., Jackson, Jordan, Wren, Jonathan D., Porter, Hunter, Richardson, Arlan
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397707/
https://ncbi.nlm.nih.gov/pubmed/30419258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2018.11.001
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