Caloric restriction mitigates age-associated hippocampal differential CG and non-CG methylation

Brain aging is marked by cognitive decline and susceptibility to neurodegeneration. Caloric-restriction (CR) increases neurogenesis, improves memory function, and protects from age-associated neurological disorders. Epigenetic mechanisms, including DNA methylation, are vital to normal CNS cellular a...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Hadad, Niran, Unnikrishnan, Archana, Jackson, Jordan A., Masser, Dustin R., Otalora, Laura, Stanford, David R., Richardson, Arlan, Freeman, Willard M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955819/
https://ncbi.nlm.nih.gov/pubmed/29631215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2018.03.009
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