Absence of genomic hypomethylation or regulation of cytosine-modifying enzymes with aging in male and female mice

BACKGROUND: Changes to the epigenome with aging, and DNA modifications in particular, have been proposed as a central regulator of the aging process, a predictor of mortality, and a contributor to the pathogenesis of age-related diseases. In the central nervous system, control of learning and memory...

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Detalhes bibliográficos
Publicado no:Epigenetics Chromatin
Main Authors: Hadad, Niran, Masser, Dustin R., Logan, Sreemathi, Wronowski, Benjamin, Mangold, Colleen A., Clark, Nicholas, Otalora, Laura, Unnikrishnan, Archana, Ford, Matthew M., Giles, Cory B., Wren, Jonathan D., Richardson, Arlan, Sonntag, William E., Stanford, David R., Freeman, Willard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942942/
https://ncbi.nlm.nih.gov/pubmed/27413395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-016-0080-6
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