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Focused, high accuracy 5-methylcytosine quantitation with base resolution by benchtop next-generation sequencing

BACKGROUND: The growing interest in the role of epigenetic modifications in human health and disease has led to the development of next-generation sequencing methods for whole genome analysis of DNA methylation patterns. However, many projects require targeted methylation analysis of specific genes...

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Autori principali: Masser, Dustin R, Berg, Arthur S, Freeman, Willard M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907040/
https://ncbi.nlm.nih.gov/pubmed/24279302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-6-33
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