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Shh and ZRS enhancer colocalisation is specific to the zone of polarising activity
Limb-specific Shh expression is regulated by the (∼1 Mb distant) ZRS enhancer. In the mouse, limb bud-restricted spatiotemporal Shh expression occurs from ∼E10 to E11.5 at the distal posterior margin and is essential for correct autopod formation. Here, we have analysed the higher-order chromatin co...
Shranjeno v:
| izdano v: | Development |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Company of Biologists Ltd
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5004883/ https://ncbi.nlm.nih.gov/pubmed/27402708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.139188 |
| Oznake: |
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