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Alterations to the remote control of Shh gene expression cause congenital abnormalities
Multi-species conserved non-coding elements occur in the vertebrate genome and are clustered in the vicinity of developmentally regulated genes. Many are known to act as cis-regulators of transcription and may reside at long distances from the genes they regulate. However, the relationship of conser...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3682722/ https://ncbi.nlm.nih.gov/pubmed/23650631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2012.0357 |
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