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Shh and ZRS enhancer colocalisation is specific to the zone of polarising activity
Limb-specific Shh expression is regulated by the (∼1 Mb distant) ZRS enhancer. In the mouse, limb bud-restricted spatiotemporal Shh expression occurs from ∼E10 to E11.5 at the distal posterior margin and is essential for correct autopod formation. Here, we have analysed the higher-order chromatin co...
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| Publicado no: | Development |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5004883/ https://ncbi.nlm.nih.gov/pubmed/27402708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.139188 |
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