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Sinularin Induces Apoptosis through Mitochondria Dysfunction and Inactivation of the pI3K/Akt/mTOR Pathway in Gastric Carcinoma Cells

Sinularin is an active compound isolated from the cultured soft coral Sinularia flexibilis. In this study, we investigated the effects of sinularin on two human gastric cancer cell lines, AGS and NCI-N87. Our results demonstrated that sinularin suppressed the proliferation of gastric cancer cells in...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Wu, Yu-Jen, Wong, Bing-Sang, Yea, Shu-Hao, Lu, Chi-I, Weng, Shun-Hsiang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999903/
https://ncbi.nlm.nih.gov/pubmed/27472346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md14080142
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