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Sinularin Induces Apoptosis through Mitochondria Dysfunction and Inactivation of the pI3K/Akt/mTOR Pathway in Gastric Carcinoma Cells

Sinularin is an active compound isolated from the cultured soft coral Sinularia flexibilis. In this study, we investigated the effects of sinularin on two human gastric cancer cell lines, AGS and NCI-N87. Our results demonstrated that sinularin suppressed the proliferation of gastric cancer cells in...

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Bibliografiset tiedot
Julkaisussa:Mar Drugs
Päätekijät: Wu, Yu-Jen, Wong, Bing-Sang, Yea, Shu-Hao, Lu, Chi-I, Weng, Shun-Hsiang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999903/
https://ncbi.nlm.nih.gov/pubmed/27472346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md14080142
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