PI3K/Akt/mTOR inhibitors in breast cancer

Activation of the phosphoinositide 3 kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway is common in breast cancer. There is preclinical data to support inhibition of the pathway, and phase I to III trials involving inhibitors of the pathway have been or are being conducted in solid tumo...

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Bibliografiske detaljer
Udgivet i:Cancer Biol Med
Main Authors: Lee, Joycelyn JX, Loh, Kiley, Yap, Yoon-Sim
Format: Artigo
Sprog:Inglês
Udgivet: Chinese Anti-Cancer Association 2015
Fag:
Review Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706528/
https://ncbi.nlm.nih.gov/pubmed/26779371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7497/j.issn.2095-3941.2015.0089
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