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Targeting PI3K/Akt/mTOR Signaling in Cancer

The phosphatidylinositol-3-kinase (PI3K)/Akt and the mammalian target of rapamycin (mTOR) signaling pathways are two pathways crucial to many aspects of cell growth and survival, in physiological as well as in pathological conditions (e.g., cancer). Indeed, they are so interconnected that, in a cert...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Porta, Camillo, Paglino, Chiara, Mosca, Alessandra
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995050/
https://ncbi.nlm.nih.gov/pubmed/24782981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00064
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