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Targeting PI3K/Akt/mTOR Signaling in Cancer

The phosphatidylinositol-3-kinase (PI3K)/Akt and the mammalian target of rapamycin (mTOR) signaling pathways are two pathways crucial to many aspects of cell growth and survival, in physiological as well as in pathological conditions (e.g., cancer). Indeed, they are so interconnected that, in a cert...

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Detalhes bibliográficos
Main Authors: Porta, Camillo, Paglino, Chiara, Mosca, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995050/
https://ncbi.nlm.nih.gov/pubmed/24782981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00064
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