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Targeting the PI3K/Akt/mTOR signalling pathway in Cystic Fibrosis
Deletion of phenylalanine 508 of the cystic fibrosis transmembrane conductance regulator (ΔF508 CFTR) is a major cause of cystic fibrosis (CF), one of the most common inherited childhood diseases. ΔF508 CFTR is a trafficking mutant that is retained in the endoplasmic reticulum (ER) and unable to rea...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5550428/ https://ncbi.nlm.nih.gov/pubmed/28794469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06588-z |
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