PI3K/Akt/mTOR signaling pathway and targeted therapy for glioblastoma

Glioblastoma multiform (GBM) is the most common malignant glioma of all the brain tumors and currently effective treatment options are still lacking. GBM is frequently accompanied with overexpression and/or mutation of epidermal growth factor receptor (EGFR), which subsequently leads to activation o...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Li, Xiaoman, Wu, Changjing, Chen, Nianci, Gu, Huadi, Yen, Allen, Cao, Liu, Wang, Enhua, Wang, Liang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
Onderwerpen:
Review
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078108/
https://ncbi.nlm.nih.gov/pubmed/26967052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7961
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