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PI3K/Akt/mTOR signaling pathway and targeted therapy for glioblastoma
Glioblastoma multiform (GBM) is the most common malignant glioma of all the brain tumors and currently effective treatment options are still lacking. GBM is frequently accompanied with overexpression and/or mutation of epidermal growth factor receptor (EGFR), which subsequently leads to activation o...
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| Publié dans: | Oncotarget |
|---|---|
| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Impact Journals LLC
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5078108/ https://ncbi.nlm.nih.gov/pubmed/26967052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7961 |
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