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PI3K/Akt/mTOR signaling pathway and targeted therapy for glioblastoma

Glioblastoma multiform (GBM) is the most common malignant glioma of all the brain tumors and currently effective treatment options are still lacking. GBM is frequently accompanied with overexpression and/or mutation of epidermal growth factor receptor (EGFR), which subsequently leads to activation o...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Xiaoman, Wu, Changjing, Chen, Nianci, Gu, Huadi, Yen, Allen, Cao, Liu, Wang, Enhua, Wang, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078108/
https://ncbi.nlm.nih.gov/pubmed/26967052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7961
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