PI3K/Akt/mTOR signaling pathway and targeted therapy for glioblastoma

Glioblastoma multiform (GBM) is the most common malignant glioma of all the brain tumors and currently effective treatment options are still lacking. GBM is frequently accompanied with overexpression and/or mutation of epidermal growth factor receptor (EGFR), which subsequently leads to activation o...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Li, Xiaoman, Wu, Changjing, Chen, Nianci, Gu, Huadi, Yen, Allen, Cao, Liu, Wang, Enhua, Wang, Liang
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
Предметы:
Review
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078108/
https://ncbi.nlm.nih.gov/pubmed/26967052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7961
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