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Architecture of fully occupied GluA2 AMPA receptor – TARP complex elucidated by cryo-EM

Fast excitatory neurotransmission in the mammalian central nervous system is largely carried out by AMPA-sensitive ionotropic glutamate receptors. Localized within the postsynaptic density of glutamatergic spines, AMPA receptors are composed of heterotetrameric receptor assemblies associated with au...

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Publicat a:Nature
Autors principals: Zhao, Yan, Chen, Shanshuang, Yoshioka, Craig, Baconguis, Isabelle, Gouaux, Eric
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4998972/
https://ncbi.nlm.nih.gov/pubmed/27368053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature18961
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