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Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM
Glutamate-gated AMPA receptors mediate the fast component of excitatory signal transduction at chemical synapses throughout all regions of the mammalian brain. AMPA receptors are tetrameric assemblies composed of four subunits, GluA1–4. Despite decades of study, the subunit composition, subunit arra...
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| Опубликовано в: : | Science |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6701862/ https://ncbi.nlm.nih.gov/pubmed/30975770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaw8250 |
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