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Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM

Glutamate-gated AMPA receptors mediate the fast component of excitatory signal transduction at chemical synapses throughout all regions of the mammalian brain. AMPA receptors are tetrameric assemblies composed of four subunits, GluA1–4. Despite decades of study, the subunit composition, subunit arra...

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Bibliografske podrobnosti
izdano v:Science
Main Authors: Zhao, Yan, Chen, Shanshuang, Swensen, Adam C., Qian, Wei-Jun, Gouaux, Eric
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701862/
https://ncbi.nlm.nih.gov/pubmed/30975770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaw8250
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