Activation and desensitization mechanism of AMPA receptor – TARP complex by cryo-EM

AMPA receptors mediate fast excitatory neurotransmission in the mammalian brain and transduce the binding of presynaptically released glutamate to the opening of a transmembrane cation channel. Within the postsynaptic density, however, AMPA receptors coassemble with transmembrane AMPA receptor regul...

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Vydáno v:Cell
Hlavní autoři: Chen, Shanshuang, Zhao, Yan, Wang, Yuhang (Steven), Shekhar, Mrinal, Tajkhorshid, Emad, Gouaux, Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621841/
https://ncbi.nlm.nih.gov/pubmed/28823560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.07.045
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