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Activation and desensitization mechanism of AMPA receptor – TARP complex by cryo-EM
AMPA receptors mediate fast excitatory neurotransmission in the mammalian brain and transduce the binding of presynaptically released glutamate to the opening of a transmembrane cation channel. Within the postsynaptic density, however, AMPA receptors coassemble with transmembrane AMPA receptor regul...
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| Publicado en: | Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5621841/ https://ncbi.nlm.nih.gov/pubmed/28823560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.07.045 |
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