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Elucidation of AMPA receptor-stargazin complexes by cryo-electron microscopy

AMPA-subtype ionotropic glutamate receptors (AMPARs) mediate fast excitatory neurotransmission, and contribute to high cognitive processes such as learning and memory. In the brain, AMPAR trafficking, gating, and pharmacology is tightly controlled by transmembrane AMPAR regulatory proteins (TARPs)....

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Twomey, Edward C., Yelshanskaya, Maria V., Grassucci, Robert A., Frank, Joachim, Sobolevsky, Alexander I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125255/
https://ncbi.nlm.nih.gov/pubmed/27365450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf8411
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