Channel opening and gating mechanism in AMPA-subtype glutamate receptors

AMPA-subtype ionotropic glutamate receptors mediate fast excitatory neurotransmission throughout the central nervous system. Gated by the neurotransmitter glutamate, AMPA receptors are critical for synaptic strength and dysregulation of AMPA receptor-mediated signaling is linked to numerous neurolog...

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Udgivet i:Nature
Main Authors: Twomey, Edward C., Yelshanskaya, Maria V., Grassucci, Robert A., Frank, Joachim, Sobolevsky, Alexander I.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743206/
https://ncbi.nlm.nih.gov/pubmed/28737760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature23479
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