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Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP γ8

AMPA-type glutamate receptors (AMPARs) mediate excitatory neurotransmission, and are central regulators of synaptic plasticity, a molecular mechanism underlying learning and memory. Although AMPARs act predominantly as heteromers, structural studies have focused on homomeric assemblies. Here we pres...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Herguedas, Beatriz, Watson, Jake F., Ho, Hinze, Cais, Ondrej, García-Nafría, Javier, Greger, Ingo H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6513756/
https://ncbi.nlm.nih.gov/pubmed/30872532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aav9011
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