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Characterizing the binding and function of TARP γ8-selective AMPA receptor modulators

α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid(AMPA)-type glutamate receptors (AMPARs) are the predominant excitatory neurotransmitter receptors in the brain, where they mediate synaptic transmission and plasticity. Excessive AMPAR activation leads to diseases such as epilepsy. AMPAR propertie...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Dohrke, Jan-Niklas, Watson, Jake F., Birchall, Kristian, Greger, Ingo H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7586208/
https://ncbi.nlm.nih.gov/pubmed/32747446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014135
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