Mapping the Interaction Sites between AMPA Receptors and TARPs Reveals a Role for the Receptor N-Terminal Domain in Channel Gating

AMPA-type glutamate receptors (AMPARs) mediate fast neurotransmission at excitatory synapses. The extent and fidelity of postsynaptic depolarization triggered by AMPAR activation are shaped by AMPAR auxiliary subunits, including the transmembrane AMPAR regulatory proteins (TARPs). TARPs profoundly i...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Cais, Ondrej, Herguedas, Beatriz, Krol, Karolina, Cull-Candy, Stuart G., Farrant, Mark, Greger, Ingo H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405707/
https://ncbi.nlm.nih.gov/pubmed/25373908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.09.029
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