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Structure and organization of heteromeric AMPA-type glutamate receptors
AMPA-type glutamate receptors (AMPARs), central mediators of rapid neurotransmission and synaptic plasticity, predominantly exist as heteromers of the GluA1-4 subunits. Here we report first AMPAR heteromer structures, which deviate substantially from existing GluA2 homomers. Crystal structures of th...
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| Gepubliceerd in: | Science |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4852135/ https://ncbi.nlm.nih.gov/pubmed/26966189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad3873 |
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