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Nanotechnology Approaches to Targeting Inflammation and Excitotoxicity in a Canine Model of Hypothermic Circulatory Arrest Induced Brain Injury
BACKGROUND: Neurocognitive dysfunction and injury remain problematic following cardiac procedures requiring hypothermic circulatory arrest (HCA). Due to poor blood-brain-barrier (BBB) penetrance and toxicities associated with systemic drug therapies, clinical success has been elusive. Accordingly, w...
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| Publicat a: | Ann Thorac Surg |
|---|---|
| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4995124/ https://ncbi.nlm.nih.gov/pubmed/27154161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.athoracsur.2016.02.077 |
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