Serum Levels of Neuron-Specific UCHL1 Predict Brain Injury in a Canine Model of Hypothermic Circulatory Arrest

BACKGROUND: Ubiquitin carboxyl-terminal esterase-L1 (UCHL1) is a protein highly selectively expressed in neurons and has been linked to neurodegenerative disease in humans. We hypothesize that UCHL1 would be an effective serum biomarker for brain injury as tested in canine models of hypothermic circ...

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Main Authors: Arnaoutakis, George J., George, Timothy J., Wang, Kevin K., Wilson, Mary Ann, Allen, Jeremiah G., Robinson, Chase W., Haggerty, Kara A., Weiss, Eric S., Blue, Mary E., Talbot, C. Conover, Troncoso, Juan C., Johnston, Michael V., Baumgartner, William A.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177106/
https://ncbi.nlm.nih.gov/pubmed/21924148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2011.06.027
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