Dendrimer Brain Uptake and Targeted Therapy for Brain Injury in a Large Animal Model of Hypothermic Circulatory Arrest

[Image: see text] Treatment of brain injury following circulatory arrest is a challenging health issue with no viable therapeutic options. Based on studies in a clinically relevant large animal (canine) model of hypothermic circulatory arrest (HCA)-induced brain injury, neuroinflammation and excitot...

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Autors principals: Mishra, Manoj K., Beaty, Claude A., Lesniak, Wojciech G., Kambhampati, Siva P., Zhang, Fan, Wilson, Mary A., Blue, Mary E., Troncoso, Juan C., Kannan, Sujatha, Johnston, Michael V., Baumgartner, William A., Kannan, Rangaramanujam M.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004292/
https://ncbi.nlm.nih.gov/pubmed/24499315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn404872e
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