Conformational states of HIV-1 reverse transcriptase for nucleotide incorporation vs. pyrophosphorolysis – binding of foscarnet

HIV-1 reverse transcriptase (RT) catalytically incorporates individual nucleotides into a viral DNA strand complementing an RNA or DNA template strand; the polymerase active site of RT adopts multiple conformational and structural states while performing this task. The states associated are dNTP bin...

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Detaylı Bibliyografya
Yayımlandı:ACS Chem Biol
Asıl Yazarlar: Das, Kalyan, Balzarini, Jan, Miller, Matthew T., Maguire, Anita R., DeStefano, Jeffrey J., Arnold, Eddy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992415/
https://ncbi.nlm.nih.gov/pubmed/27192549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00187
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