Regulation of GLI underlies a role for BET bromodomains in pancreatic cancer growth and the tumor microenvironment

PURPOSE: The initiation, progression, and maintenance of pancreatic ductal adenocarcinoma (PDAC) results from the interplay of genetic and epigenetic events. While the genetic alterations of PDAC have been well characterized, epigenetic pathways regulating PDAC remain, for the most part, elusive. Th...

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Bibliografiset tiedot
Julkaisussa:Clin Cancer Res
Päätekijät: Huang, Yinshi, Nahar, Sabikun, Nakagawa, Akifumi, Fernandez de Barrena, Maite G., Mertz, Jennifer A., Bryant, Barbara M., Adams, Curtis E., Mino-Kenudson, Mari, Von Alt, Kate N., Chang, Kevin, Conery, Andrew R., Hatton, Charlie, Sims, Robert J., Fernandez-Zapico, Martin E., Wang, Xingpeng, Lillemoe, Keith D., Castillo, Carlos Fernández-del, Warshaw, Andrew L., Thayer, Sarah P., Liss, Andrew S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987213/
https://ncbi.nlm.nih.gov/pubmed/27169995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2068
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