Regulation of GLI underlies a role for BET bromodomains in pancreatic cancer growth and the tumor microenvironment

PURPOSE: The initiation, progression, and maintenance of pancreatic ductal adenocarcinoma (PDAC) results from the interplay of genetic and epigenetic events. While the genetic alterations of PDAC have been well characterized, epigenetic pathways regulating PDAC remain, for the most part, elusive. Th...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Huang, Yinshi, Nahar, Sabikun, Nakagawa, Akifumi, Fernandez de Barrena, Maite G., Mertz, Jennifer A., Bryant, Barbara M., Adams, Curtis E., Mino-Kenudson, Mari, Von Alt, Kate N., Chang, Kevin, Conery, Andrew R., Hatton, Charlie, Sims, Robert J., Fernandez-Zapico, Martin E., Wang, Xingpeng, Lillemoe, Keith D., Castillo, Carlos Fernández-del, Warshaw, Andrew L., Thayer, Sarah P., Liss, Andrew S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987213/
https://ncbi.nlm.nih.gov/pubmed/27169995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2068
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