5‐HT (2B) receptor antagonists attenuate myofibroblast differentiation and subsequent fibrotic responses in vitro and in vivo

Pulmonary fibrosis is characterized by excessive accumulation of connective tissue, along with activated extracellular matrix (ECM)‐producing cells, myofibroblasts. The pathological mechanisms are not well known, however serotonin (5‐HT) and 5‐HT class 2 (5‐HT (2)) receptors have been associated wit...

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Enregistré dans:
Détails bibliographiques
Publié dans:Physiol Rep
Auteurs principaux: Löfdahl, Anna, Rydell‐Törmänen, Kristina, Müller, Catharina, Martina Holst, C., Thiman, Lena, Ekström, Gunilla, Wenglén, Christina, Larsson‐Callerfelt, Anna‐Karin, Westergren‐Thorsson, Gunilla
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985542/
https://ncbi.nlm.nih.gov/pubmed/27482070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12873
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