5‐HT (2B) receptor antagonists attenuate myofibroblast differentiation and subsequent fibrotic responses in vitro and in vivo

Pulmonary fibrosis is characterized by excessive accumulation of connective tissue, along with activated extracellular matrix (ECM)‐producing cells, myofibroblasts. The pathological mechanisms are not well known, however serotonin (5‐HT) and 5‐HT class 2 (5‐HT (2)) receptors have been associated wit...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Löfdahl, Anna, Rydell‐Törmänen, Kristina, Müller, Catharina, Martina Holst, C., Thiman, Lena, Ekström, Gunilla, Wenglén, Christina, Larsson‐Callerfelt, Anna‐Karin, Westergren‐Thorsson, Gunilla
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985542/
https://ncbi.nlm.nih.gov/pubmed/27482070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12873
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