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5‐HT (2B) receptor antagonists attenuate myofibroblast differentiation and subsequent fibrotic responses in vitro and in vivo

Pulmonary fibrosis is characterized by excessive accumulation of connective tissue, along with activated extracellular matrix (ECM)‐producing cells, myofibroblasts. The pathological mechanisms are not well known, however serotonin (5‐HT) and 5‐HT class 2 (5‐HT (2)) receptors have been associated wit...

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Bibliographische Detailangaben
Veröffentlicht in:Physiol Rep
Hauptverfasser: Löfdahl, Anna, Rydell‐Törmänen, Kristina, Müller, Catharina, Martina Holst, C., Thiman, Lena, Ekström, Gunilla, Wenglén, Christina, Larsson‐Callerfelt, Anna‐Karin, Westergren‐Thorsson, Gunilla
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985542/
https://ncbi.nlm.nih.gov/pubmed/27482070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12873
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