Defective alterations in the collagen network to prostacyclin in COPD lung fibroblasts

BACKGROUND: Prostacyclin analogs are potent vasodilators and possess anti-inflammatory properties. However, the effect of prostacyclin on extracellular matrix (ECM) in COPD is not well known. Collagen fibrils and proteoglycans are essential ECM components in the lung and fibroblasts are key players...

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Detalhes bibliográficos
Main Authors: Larsson-Callerfelt, Anna-Karin, Hallgren, Oskar, Andersson-Sjöland, Annika, Thiman, Lena, Björklund, Johan, Kron, Josefine, Nihlberg, Kristian, Bjermer, Leif, Löfdahl, Claes-Göran, Westergren-Thorsson, Gunilla
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585859/
https://ncbi.nlm.nih.gov/pubmed/23406566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-14-21
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