Enhanced ROCK1 dependent contractility in fibroblast from chronic obstructive pulmonary disease patients

BACKGROUND: During wound healing processes fibroblasts account for wound closure by adopting a contractile phenotype. One disease manifestation of COPD is emphysema which is characterized by destruction of alveolar walls and our hypothesis is that fibroblasts in the COPD lungs differentiate into a m...

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Autori principali: Hallgren, Oskar, Rolandsson, Sara, Andersson-Sjöland, Annika, Nihlberg, Kristian, Wieslander, Elisabet, Kvist-Reimer, Martina, Dahlbäck, Magnus, Eriksson, Leif, Bjermer, Leif, Erjefält, Jonas S, Löfdahl, Claes-Göran, Westergren-Thorsson, Gunilla
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477051/
https://ncbi.nlm.nih.gov/pubmed/22913419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-10-171
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