5‐HT (2B) receptor antagonists attenuate myofibroblast differentiation and subsequent fibrotic responses in vitro and in vivo

Pulmonary fibrosis is characterized by excessive accumulation of connective tissue, along with activated extracellular matrix (ECM)‐producing cells, myofibroblasts. The pathological mechanisms are not well known, however serotonin (5‐HT) and 5‐HT class 2 (5‐HT (2)) receptors have been associated wit...

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Pubblicato in:Physiol Rep
Autori principali: Löfdahl, Anna, Rydell‐Törmänen, Kristina, Müller, Catharina, Martina Holst, C., Thiman, Lena, Ekström, Gunilla, Wenglén, Christina, Larsson‐Callerfelt, Anna‐Karin, Westergren‐Thorsson, Gunilla
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985542/
https://ncbi.nlm.nih.gov/pubmed/27482070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12873
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