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Absence of fibromodulin affects matrix composition, collagen deposition and cell turnover in healthy and fibrotic lung parenchyma

The ECM exerts great effects on cells, and changed composition may therefore have profound impact. Small leucine-rich proteoglycans, e.g. fibromodulin, are essential in collagen assembly. Our aim was to investigate the role of fibromodulin in healthy and fibrotic lung parenchyma, theorizing that fib...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rydell-Törmänen, Kristina, Andréasson, Kristofer, Hesselstrand, Roger, Westergren-Thorsson, Gunilla
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377322/
https://ncbi.nlm.nih.gov/pubmed/25230586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06383
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