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Absence of fibromodulin affects matrix composition, collagen deposition and cell turnover in healthy and fibrotic lung parenchyma

The ECM exerts great effects on cells, and changed composition may therefore have profound impact. Small leucine-rich proteoglycans, e.g. fibromodulin, are essential in collagen assembly. Our aim was to investigate the role of fibromodulin in healthy and fibrotic lung parenchyma, theorizing that fib...

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Pubblicato in:Sci Rep
Autori principali: Rydell-Törmänen, Kristina, Andréasson, Kristofer, Hesselstrand, Roger, Westergren-Thorsson, Gunilla
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377322/
https://ncbi.nlm.nih.gov/pubmed/25230586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06383
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